Target-Controlled Versus Manually-Controlled Infusion of Propofol for Direct Laryngoscopy and Bronchoscopy

Abstract

This study compares the clinical profile of propofol anesthesia for direct laryngoscopy with spontaneous ventilation when the drug is administered either as a manually controlled infusion or by targeting the effect-site concentration through a target-controlled infusion (TCI) device. TCI improves the time course of propofol effects.