pH-Responsive Molecular Nanocarriers Based on Dendritic Core-Shell Architectures

Abstract

A simple and efficient concept has been developed for the synthesis of pH-responsive molecular nanocarriers based on commercially available hyperbranched polymers. These dendritic core-shell architectures can encapsulate, transport, and selectively release polar guest molecules in an acidic environment (pH 3–6, see scheme). The observed release properties render these molecular nanocarriers promising candidates for controlled drug and gene delivery. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z19603_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.