Concepedia

A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

Zhenning Sun, Fengqin Liu, Yan Chen, Paul Kwong Hang Tam, Dan Yang

Organic Letters · 2008 · 335 citations · 14 references

DOI

Abstract

A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl(-) system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems.

References

14

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Gilles Ulrich, Raymond Ziessel, Anthony Harriman · Angewandte Chemie International Edition · 2007 · 3.1K citations

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Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species

Ken‐ichi Setsukinai, Yasuteru Urano, Katsuko Kakinuma et al. · Journal of Biological Chemistry · 2003 · 1.3K citations · Full text

Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

Seigo Sugiyama, Yoshikatsu Okada, Galina K. Sukhova et al. · American Journal Of Pathology · 2001 · 697 citations

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Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene ChromophoreRational Design of Potentially Useful Bioimaging Fluorescence Probe

Yu Gabe, Yasuteru Urano, Kazuya Kikuchi et al. · Journal of the American Chemical Society · 2004 · 657 citations

Chlorinative stress: An under appreciated mediator of neurodegeneration?

Yann Wan Yap, Matthew Whiteman, Nam Sang Cheung · Cellular Signalling · 2006 · 568 citations

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