Palladium‐Catalyzed Coupling Reactions for the Functionalization of BODIPY Dyes with Fluorescence Spanning the Visible Spectrum

Abstract

Abstract The BODIPY fluorophore can easily be functionalized at the 3‐ (and 5‐)position(s) with one or two aryl, ethenylaryl and ethynylaryl moieties by palladium‐catalyzed coupling reactions of the 3,5‐dichloroBODIPY derivative using the Stille, Suzuki, Heck and Sonogashira reactions. The fluorescence excitation and emission spectral maxima of the novel BODIPY derivatives range from green to near‐infrared. The new class of ethynylaryl‐substituted BODIPY dyes are extremely bright fluorescent compounds.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)