Short communication Interleukin-6 levels in cerebrospinal fluid inversely correlate to severity of Parkinson's disease

Abstract

Elevated IL-6 levels in the CSF of untreated parkinsonian patients may reflect the original condition in the course of disease. We speculate that an endogenous upregulation of IL-6 synthesis occurs in order to regenerate lesioned neurons probably at an early phase of the degenerative process in PD.