Publication | Closed Access
The reaction of Tetrazole with Phosphoramidites as a Model for the Nucleotide Coupling Step
18
Citations
9
References
1988
Year
Nucleotide Coupling StepBioorganic ChemistryBiochemistryTetrazole-activated Coupling StepNatural SciencesBioconjugationOligonucleotideMolecular BiologyReaction IntermediateClick ChemistryStructure-function Enzyme KineticsModel ReactionsBiomolecular EngineeringBio-orthogonal Chemistry
Abstract The mechanism of the tetrazole-activated coupling step in the synthesis of oligonucleotides via phosphorami-dites is studied with the help of model reactions.
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