Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study

C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women

Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine · 2000 · 5.9K citations · Full text

Medicine, Cardiology, Clinical Sciences +15

Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis

Claire Bombardier, Loren Laine, Alise Reicin et al. · New England Journal of Medicine · 2000 · 4K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +8

Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2

Brendan McAdam, Francesca Catella-Lawson, Issam A. Mardini et al. · Proceedings of the National Academy of Sciences · 1999 · 1.3K citations

Medicine, Pharmacology, Pharmacotherapy +13

Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk

The Lancet · 1998 · 796 citations

Medicine, Cardiology, Pharmacotherapy +10

Nonsteroidal Anti-inflammatory Drug Use and Increased Risk for Peptic Ulcer Disease in Elderly Persons

Marie R. Griffin, Joyce M. Piper, James R. Daugherty et al. · Annals of Internal Medicine · 1991 · 767 citations

Medicine, Geriatric Medicine, Pharmacology +11