Constrained amino acids. An approach to the synthesis of 3-substituted prolines

Simple stereoselective version of the Claisen rearrangement leading to trans-trisubstituted olefinic bonds. Synthesis of squalene

William S. Johnson, Lucius Werthemann, William R. Bartlett et al. · Journal of the American Chemical Society · 1970 · 629 citations

Natural Sciences, Chemistry, Natural Product Biosynthesis +8

The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acids

David A. Evans, Thomas C. Britton, Jonathan A. Ellman et al. · Journal of the American Chemical Society · 1990 · 451 citations

Natural Sciences, Chemistry, Organic Chemistry +13

Synthesis of the cyclic hexapeptide echinocandin D. New approaches to the asymmetric synthesis of .beta.-hydroxy .alpha.-amino acids

David A. Evans, Ann E. Weber · Journal of the American Chemical Society · 1987 · 197 citations

Natural Sciences, Biochemistry, Chemistry +11

A new method for the preparation of tertiary butyl ethers and esters

Alan Armstrong, Ian Brackenridge, Richard F. W. Jackson et al. · Tetrahedron Letters · 1988 · 180 citations

Natural Sciences, Chemistry, Medicinal Chemistry +4

Selective Removal of an N-BOC Protecting Group in the Presence of a tert-Butyl Ester and Other Acid-Sensitive Groups

Frank S. Gibson, Stephen C. Bergmeier, Henry Rapoport · The Journal of Organic Chemistry · 1994 · 111 citations

Natural Sciences, Chemistry, Analytical Chemistry +9