Antitumor and toxicity evaluation of free doxorubicin and doxorubicin entrapped in cardiolipin liposomes

A clinicopathologic analysis of adriamycin cardiotoxicity

Edward A. Lefrak, Jan Piťha, Sidney Rosenheim et al. · Cancer · 1973 · 1.6K citations

Medicine, Cardiology, Pharmacology +16

PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS

Ruth I. Geran, Nathaniel H. Greenberg, Marylea MacDonald et al. · Cancer chemotherapy reports. Part 1 · 1972 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +8

Evidence of a specific complex between adriamycin and negatively-charged phospholipids

Erik Goormaghtigh, Pierre Chatelain, J. Caspers et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1980 · 312 citations

Natural Sciences, Biochemistry, Biophysics +13

Liposomes as in vivo carriers of adriamycin: reduced cardiac uptake and preserved antitumor activity in mice.

Alberto Gabizón, Amir Dagan, Dorit Goren et al. · PubMed · 1982 · 262 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Clinical spectrum of anthracycline antibiotic cardiotoxicity.

Bristow Mr, Billingham Me, Mason Jw et al. · PubMed · 1978 · 252 citations

Medicine, Cardiology, Pharmacology +17