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The Crystal Structure of E.coli 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase in a Ternary Complex with the Antimalarial Compound Fosmidomycin and NADPH Reveals a Tight-binding Closed Enzyme Conformation

Crystal StructureE.coli 1-Deoxy-d-xylulose-5-phosphate ReductoisomeraseBiochemistryNatural SciencesEnzyme CatalysisProtein X-ray CrystallographyMolecular BiologyEnzyme ConformationStructure-function Enzyme KineticsStructural Biology