A Fluorescent Ratiometric Chemodosimeter for Cu²⁺ Based on TBET and Its Application in Living Cells

Abstract

Based on a through bond energy transfer (TBET) between Rhodamine and a naphthalimide fluorophore, a fluorescent ratiometric chemodosimeter RN1 was designed and prepared for single selective detection of Cu(2+) in aqueous solution and in living cells, as Cu(2+) acts as not only a selective recognizing guest but also a hydrolytic promoter.