Association between Expression of Vascular Endothelial Growth Factor C, Chemokine Receptor CXCR4 and Lymph Node Metastasis in Colorectal Cancer

Abstract

This study suggests that although the mechanism that promoted lymph node metastasis was different between VEGF-C and CXCR4, both VEGF-C and CXCR4 contributed to lymphatic involvement and nodal metastasis in colorectal cancer.