MN1 overexpression is an important step in the development of inv(16) AML

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Koichi Akashi, David Traver, Toshihiro Miyamoto et al. · Nature · 2000 · 2.6K citations

Life Sciences, Biology, Cell Biology +12

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

Tsukasa Okuda, Jan M. van Deursen, Scott W. Hiebert et al. · Cell · 1996 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia

Peter J.M. Valk, Roel G.W. Verhaak, M. Antoinette Beijen et al. · New England Journal of Medicine · 2004 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

Todd R. Golub, George F. Barker, Michael Lovett et al. · Cell · 1994 · 1.2K citations

Medicine, Genetics, Molecular Genetics +17

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Qing Wang, Terryl Stacy, Michael Binder et al. · Proceedings of the National Academy of Sciences · 1996 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +14