WIMAGINE: Wireless 64-Channel ECoG Recording Implant for Long Term Clinical Applications

TLDR

WIMAGINE is a wireless 64‑channel ECoG implant designed for clinical use, meeting safety, reliability, and class III AIMD regulatory requirements. The device is intended to interface a cortical electrode array with an external computer for neural recording and control, and its main features, architecture, functional performance, and long‑term biocompatibility are presented. It is powered via a 13.56 MHz inductive link delivering up to 100 mW and wirelessly transmits digitized data to a custom base station connected to a PC. The implant records 64‑channel neural activity with selectable gain and sampling frequency, achieving <1 µV RMS noise in 0.5–300 Hz, and its hermetic housing and antennae are optimized to facilitate surgery.

Abstract

A wireless 64-channel ElectroCorticoGram (ECoG) recording implant named WIMAGINE has been designed for various clinical applications. The device is aimed at interfacing a cortical electrode array to an external computer for neural recording and control applications. This active implantable medical device is able to record neural activity on 64 electrodes with selectable gain and sampling frequency, with less than 1 μV(RMS) input referred noise in the [0.5 Hz - 300 Hz] band. It is powered remotely through an inductive link at 13.56 MHz which provides up to 100 mW. The digitized data is transmitted wirelessly to a custom designed base station connected to a PC. The hermetic housing and the antennae have been designed and optimized to ease the surgery. The design of this implant takes into account all the requirements of a clinical trial, in particular safety, reliability, and compliance with the regulations applicable to class III AIMD. The main features of this WIMAGINE implantable device and its architecture are presented, as well as its functional performances and long-term biocompatibility results.