Radiology · 1985 · 103 citations · 0 references
MedicineOncologyRadiologyBiomedical ImagingDiagnostic ImagingDiagnostic RadiologyComputed TomographyOncologic Imaging ProtocolsOxygen TransportTumor CharacterizationTumor ImagingCancer ImagingComputed Tomography GuidanceOxygen Tension MeasurementOxygenation MappingTissue Oxygenation MeasurementTumor Hypoxia ImagingTumor OxygenationTumor Response Evaluation
The role of oxygen in tumor response to therapy has been studied for several decades. We describe a technique that allows in vivo measurement of oxygen in tumors using computed tomography to guide probes. In the evaluation of 16 tumors, oxygen tensions were found to be substantially lower than surrounding tissue and varied nonrandomly. This technique has allowed construction of detailed tumor oxygen level maps.