Concepedia

Synthesis and characterization of small circular double-stranded RNAs

Naoko Abe, Hiroshi Abe, Takahito Ohshiro, Yuko Nakashima, Mizuo Maeda, Yoshihiro Ito

Chemical Communications · 2010 · 19 citations · 27 references

DOI

Concepts

Abstract

Small circular double-stranded RNAs (dsRNAs) were synthesized. The structural analysis by atomic force microscopy gave direct images for the interpretation of the structural strain present in circular dsRNAs. Finally, we demonstrated that circular dsRNA caused RNAi effect in cells.

References

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RNAi

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