Transplantation · 1987 · 13 citations · 0 references
MedicineNephrologyPathologyHepatologyKidney TransplantationTransplant ImmunologyImmunosuppression In Kidney TransplantationLiver Function TestsLiver TransplantationTransplant PathologyTransplant RejectionViral HepatitisFulminant Viral HepatitisImmunofluorescence AssaysImmunofluorescence DiagnosisImmunofluorescence FindingsImmunofluorescence StainingLiver AbnormalitiesRenal Transplant Care
In a series of about 300 renal transplant patients followed from 1972 to 1983, 3 cases of fulminant hepatitis were observed in HBs Ag-positive patients. In the liver biopsies of 2/3 of them, the delta antigen was detected by direct immunofluorescence with a specific anti-delta serum. This result demonstrates the responsibility of the delta agent for the development of fulminant hepatitis, and emphasizes the possibility of delta infection in HBs Ag-positive transplant patients with severe hepatitis.