Assessment of the mutagenic, recombinagenic and carcinogenic potential of orlistat in somatic cells of Drosophila melanogaster

The Clonal Evolution of Tumor Cell Populations

Peter C. Nowell̀ · Science · 1976 · 6.5K citations

Medicine, Genetics, Oncology +17

The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation.

Robin W. Justice, Olav Zilian, Daniel F. Woods et al. · Genes & Development · 1995 · 969 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Somatic mutation and recombination test in <i>Drosophila melanogaster</i>

Ulrich Gräf, F.E. Würgler, Alan J. Katz et al. · Environmental Mutagenesis · 1984 · 674 citations

Life Sciences, Entomology, Toxicology +17

Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity

Steven J. Kridel, Fumiko Axelrod, Natasha Rozenkrantz et al. · Cancer Research · 2004 · 601 citations · Full text

Medicine, Oncology, Pharmacology +16

Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination tests (SMART) in Drosophila

H. Frei, F.E. Würgler · Mutation Research/Environmental Mutagenesis and Related Subjects · 1995 · 219 citations

Public Health, Biostatistics, Genetics +12