Hypoxia induces apoptosis and autophagic cell death in human periodontal ligament cells through <scp>HIF</scp>‐1α pathway

Abstract

Our data showed that CoCl(2) could induce cytotoxicity through mitochondria- apoptotic and autophagic pathways involved in HIF-1α. CoCl(2 -treated PDLCs may serve as an in vitro model for studies of molecular mechanisms in periodontitis.