Toll‐like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll‐like receptor 9 drives Th1 autoimmunity in murine vasculitis - Concepedia

Concepedia

Publication | Closed Access

Toll‐like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll‐like receptor 9 drives Th1 autoimmunity in murine vasculitis

70

Citations

30

References

2010

Year

Shaun A. Summers, Oliver M. Steinmetz, Poh‐Yi Gan, Joshua D. Ooi, Dragana Odobasic, A. Richard Kitching, Stephen R. Holdsworth

Arthritis & Rheumatism

Abstract

Our findings indicate a pathogenic role of TLRs in initiating autoimmune AAV. TLR-2 induces Th17 CD4 cells while TLR-9 can also direct vasculitis, by directing Th1 autoimmunity.

References

	Year	Citations

Page 1