Green Nanobiotechnology: Factors Affecting Synthesis and Characterization Techniques

TLDR

Nanobiotechnology enables the conversion of metals into nanoscale particles, altering their chemical, physical, and optical properties, yet current synthesis methods are costly, environmentally damaging, and inefficient, prompting focus on green strategies that consider factors such as pH, temperature, and particle size to optimize quality and applicability. This review aims to examine the parameters influencing green nanobiotechnology synthesis and the characterization techniques employed for biomedical and environmental applications. It surveys the various green synthesis parameters and characterization methods used to evaluate nanoparticle quality and suitability for drug delivery and environmental remediation.

Abstract

Nanobiotechnology is gaining tremendous impetus in this era owing to its ability to modulate metals into their nanosize, which efficiently changes their chemical, physical, and optical properties. Accordingly, considerable attention is being given to the development of novel strategies for the synthesis of different kinds of nanoparticles of specific composition and size using biological sources. However, most of the currently available techniques are expensive, environmentally harmful, and inefficient with respect to materials and energy use. Several factors such as the method used for synthesis, pH, temperature, pressure, time, particle size, pore size, environment, and proximity greatly influence the quality and quantity of the synthesized nanoparticles and their characterization and applications. Additionally, characterization of the synthesized nanoparticles is essential to their potential use in various drug delivery and biomedical applications. The present review highlights various parameters affecting the synthesis of nanoparticles by green nanobiotechnology and different techniques used for characterizing the nanoparticles for their potential use in biomedical and environmental applications.