Successful Isolation of Liver Progenitor Cells by Aldehyde Dehydrogenase Activity in Na"ve Mice

Abstract

High ALDH activity is a feature of LPCs that can be taken advantage of to isolate these cells from untreated mouse as well as human liver tissues. This novel protocol is practically relevant, because it provides an easy and nontoxic method to isolate liver stem cells from normal tissue for potential therapeutic purposes.