Exocrine pancreatic function in hepatocyte nuclear factor 1β‐maturity‐onset diabetes of the young (<scp>HNF</scp>1B‐<scp>MODY</scp>) is only moderately reduced: compensatory hypersecretion from a hypoplastic pancreas

Abstract

Carriers of the HNF1B mutation have lower exocrine pancreatic function involving both ductal and acinar cells. Compensatory hypersecretion suggests that the small pancreas of HNF1B mutation carriers is attributable to hypoplasia, not atrophy.