Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Repetitive Action Potentials in Isolated Nerve Terminals in the Presence of 4‐Aminopyridine: Effects on Cytosolic Free Ca²⁺ and Glutamate Release

Gareth R. Tibbs, Anne Barrie, F. J. E. Van Mieghem et al. · Journal of Neurochemistry · 1989 · 301 citations

Life Sciences, Neurobiology, Neuroscience +17

Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na + channels, Ca 2+ channels, and GABA A receptors

Ratnakumari Lingamaneni, Hugh C. Hemmings · British Journal of Anaesthesia · 2003 · 103 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Vinpocetine is as potent as phenytoin to block voltage-gated Na+ channels in rat cortical neurons

Péter Molnár, Sándor L. Erdö · European Journal of Pharmacology · 1995 · 64 citations

Natural Sciences, Neuroscience, Pharmacology +13

Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels11Abbreviations: AED, antiepileptic drug; CBZ, carbamazepine; OXC, oxcarbazepine; and 4-AP, 4-aminopyridine.

António Francisco Ambrósio, Ana Paula Silva, João O. Malva et al. · Biochemical Pharmacology · 2001 · 52 citations · Full text

Medicine, Neuroscience, Pharmacology +17