Left Ventricular Electromechanical Mapping to Assess Efficacy of phVEGF ₁₆₅ Gene Transfer for Therapeutic Angiogenesis in Chronic Myocardial Ischemia

Abstract

The results of EMM constitute objective evidence that phVEGF(165) GTx augments perfusion of ischemic myocardium. These findings, together with reduction in the size of the defects documented at rest by serial single-photon emission CT-sestamibi imaging, suggest that phVEGF(165) GTx may successfully rescue foci of hibernating myocardium.