Concepedia

Publication | Closed Access

<i>UGT1A1*28</i> Genotype Predicts Gastrointestinal Toxicity in Patients Treated With Intermediate-Dose Irinotecan

DOI

34

Citations

20

References

2009

Year

Roberta Ferraldeschi, Laura J Minchell, Stephen A. Roberts, Simon Tobi, Kristen D. Hadfield, Fiona Blackhall, Saifee Mullamitha, G. Wilson, Juan W. Valle, Mark Saunders,
Pharmacogenomics

Abstract

Our findings indicate that UGT1A1 genotyping is not a good predictor of hematological toxicity in patients treated with intermediate irinotecan doses. However, it may be useful in the identification of patients at risk of severe diarrhea.

References

YearCitations

Page 1