Publication | Closed Access
Optical super-resolution by high-index liquid-immersed microspheres
334
Citations
23
References
2012
Year
EngineeringMicroscopyBiomedical EngineeringMicro-optical ComponentSuper-resolution MicroscopySuper-resolution ImagingMicroscopy MethodOptical PropertiesMaterials FabricationMicron-scale MicrospheresOptical Super-resolutionBioimagingLight MicroscopyMicrofluidicsBiophysicsNanophotonicsPhysicsSuper-resolutionComputational Optical ImagingNano ScaleBiomedical DiagnosticsImaging TechniqueApplied PhysicsBiomedical ImagingNanofabricationMedicine
It is experimentally shown that barium titanate glass microspheres with diameters (D) in the range 2–220 μm and with high refractive index (n ∼ 1.9–2.1) can be used for super-resolution imaging of liquid-immersed nanostructures. Using micron-scale microspheres, we demonstrate an ability to discern the shape of a pattern with a minimum feature size of ∼λ/7, where λ is the illumination wavelength. For spheres with D > 50 μm, the discernible feature sizes were found to increase to ∼λ/4. Detailed data on the resolution, magnification, and field-of-view are presented. This imaging technique can be used in biomedical microscopy, microfluidics, and nanophotonics applications.
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