Epiphysiometaphyseal changes in children after severe meningococcic sepsis

Abstract

We studied three children with severe forms of meningo coccic sepsis and intravascular coagulation having exten sive cutaneous necrosis during their acute illness.After 1 year, two of them showed epiphysiometaphyseal abnormal ities limited to the lower limbs with bowing of the legs and secondary dwarfism.In the third case, bilateral abnonmali ties appeared 4 months after the sepsis and involved the distal tibia, fibula, and talus, as well as the left tansal navic ular.These lesions are extremely rare and to our knowledge have not been reported previously. Case ReportsCase 1A 7-month-oldboywasadmittedbecauseof 5 hr of restlessness and high fever.He was pale and responded only to painful stimuli.His temperature was 39.5°C; blood pressure, 75/30 mm Hg; white