Chemistry - A European Journal · 1999 · 31 citations · 0 references
Natural SciencesBiophysicsChemistryBiophysical ChemistryMolecular BiophysicsMolecular ImagingBiomolecular StructureFluorescence SpectroscopyHydrogen Bonding In BiomoleculesMacromolecular StructureMolecular Probe DevelopmentPhotophysics Of Fluorescent ProbesFluorescent Chemical ProbesFluorescent DyesFluorescent ProbesHydrophobic BondingIntramolecular Hydrogen BondingNanocavities
Encapsulating the dye 2-(2′-hydroxyphenyl)-4-methyloxazole in hydrophobic molecular cavities leads to a sequestered form with an intramolecular hydrogen bond (see picture). Since the position and anisotropy of the emission band of this species depend on the freedom of rotation about the C2−C1′ bond, it can be used to obtain information on the size of hydrophobic nanocavities in chemical and biological systems.