Wound Edge Microvascular Blood Flow during Negative-Pressure Wound Therapy: Examining the Effects of Pressures from –10 to –175 mmHg

Abstract

Blood flow changes gradually when the negative pressure is increased. The levels of pressure for negative-pressure wound therapy may be tailored depending on the wound type and tissue composition, and this study implies that -80 mmHg has similar blood flow effects as the clinical standard, -125 mmHg.