Conjunctival vaccination of the brushtail possum (<i>Trichosurus vulpecula</i>) with bacille Calmette-Guérin

Abstract

Conjunctival vaccination with BCG induced a significant level of protective immunity against M. bovis infection in possums. This route of vaccination, together with intranasal aerosol vaccination, could be utilised in the delivery of an aerosolised vaccine using a device that sprays the vaccine suspension into the eyes and nose of possums.