Soft Matter · 2009 · 262 citations · 80 references
MedicineBiomedical EngineeringPharmaceuticsDrug DeliveryUltrasonographyUltrasoundContrast-enhanced UltrasoundUltrasonicsUltrasound ImagingUltrasound PhysicsUltrasound-guided ProceduresDrug Delivery ImagingMicrobubble FormationUltrasound Contrast AgentsUltrasound-mediated PermeationUltrasound-responsive ReleaseUltrasound-triggered Release
Ultrasound imaging is widely used in both diagnosis of diseases and pregnancy follow-up. As ultrasound imaging is a harmless, cheap and portable technique, ultrasound guided drug delivery is gaining more and more attention in the drug delivery field. To be effective, in most cases, ultrasonic drug delivery makes use of microbubbles. This highlight describes why it is attractive to load the microbubbles with drugs and discusses recent attempts made in the design of drug loaded microbubbles.
80
Membrane disruption by optically controlled microbubble cavitation
Paul Prentice, A. Cuschieri, Kishan Dholakia et al. · Nature Physics · 2005 · 581 citations · Full text