The Protein Truncation Test (PTT) as a Method of Detection for Choroideremia Mutations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.9K citations

Life Sciences, Biochemistry, Molecular Biology +12

Cloning of a gene that is rearranged in patients with choroideraemia

Frans P.M. Cremers, Dorien J.R. van de Pol, Liesbeth P. M. van Kerkhoff et al. · Nature · 1990 · 334 citations

Life Sciences, Genetics, Molecular Genetics +9

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

Douglas Andres, Miguel C. Seabra, Michael S. Brown et al. · Cell · 1993 · 325 citations

Life Sciences, Biochemistry, Molecular Biology +9

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.

Miguel C. Seabra, Joseph L. Goldstein, Thomas C. Südhof et al. · Journal of Biological Chemistry · 1992 · 323 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9