Elevated post‐dexamethasone suppression cortisol concentrations correlate with hormonal alterations of the hypothalamo‐pituitary adrenal axis in patients with adrenal incidentalomas

Abstract

It is concluded that higher post-low dose dexamethasone cortisol concentrations are associated with lower ACTH and dehydroepiandrosterone sulphate, higher midnight cortisol concentrations and larger adenomas. These findings are consistent with the hypothesis that post-low dose dexamethasone cortisol concentrations represent a useful index in assessing subtle glucocorticoid autonomy in patients with adrenal adenomas.