The History of Histoplasmosis, 1906 to 1956

Abstract

HISTOPLASMOSIS is a fungous disease that is almost world wide in distribution but is most frequently seen in an area of the United States roughly defined as the Mississippi Valley. Millions of persons become infected with the fungus Histoplasma capsulatum, but comparatively few show signs of the disease.The organism causing the disease is H. capsulatum, which forms small, slightly ovoid cells of 1 to 5 microns in diameter in the animal body but grows as a mold on artificial mediums at room temperature. The disease has been found in man and animal; the organism has been isolated from soil, . . .