Evaluation of Different Models of Experimentally Induced Liver Cirrhosis for MRI Research with Correlation to Histopathologic Findings

Abstract

The TAA model is easier to perform and more reliable in liver cirrhosis induction than the CCl4 models. Although there is a positive correlation between the T2 relaxation times and the degree of liver fibrosis/cirrhosis, this probably results from the associated inflammatory changes and is not caused by the increased amount of connective tissue.