Antibacterial discovery and development—the failure of success?

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

C. Kendall Stover, X. Q. Pham, Alice L. Erwin et al. · Nature · 2000 · 4.6K citations · Full text

Life Sciences, Genetics, Microbiology +13

Methicillin-Resistant <i>S. aureus</i> Infections among Patients in the Emergency Department

Gregory J. Moran, Anusha Krishnadasan, Rachel Gorwitz et al. · New England Journal of Medicine · 2006 · 2.3K citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

A Predominantly Clonal Multi-Institutional Outbreak of<i>Clostridium difficile</i>–Associated Diarrhea with High Morbidity and Mortality

Vivian G. Loo, Louise Poirier, Mark A. Miller et al. · New England Journal of Medicine · 2005 · 1.9K citations

Life Sciences, Infectious Diseases, Microbiology +17

Sampling the Antibiotic Resistome

Vanessa M. D’Costa, Katherine M. McGrann, Donald W. Hughes et al. · Science · 2006 · 1.6K citations

Life Sciences, Microbiology, Antimicrobial Resistance +16

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, S.M. Soisson, Katherine Young et al. · Nature · 2006 · 815 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9