Increased Eosinophil Infiltration and Degranulation in Colonic Tissue From Patients With Collagenous Colitis

Abstract

Eosinophil infiltration and degranulation are increased in the colonic mucosa of patients with CC compared to healthy controls. Eosinophils and their cytotoxic granule proteins could be involved in the pathogenesis of CC. Further studies will be necessary to elucidate the mechanisms of eosinophil activation in CC.