Exercise pre-conditioning reduces brain inflammation in stroke via tumor necrosis factor-<i>α</i>, extracellular signal-regulated kinase 1/2 and matrix metalloproteinase-9 activity

Abstract

These results suggest that exercise-induced up-regulation of tumor necrosis factor-alpha before stroke and extracellular signal-regulated kinase 1/2 phosphorylation play a role in decreasing brain inflammation by regulating matrix metalloproteinase-9 activity.