Anion Gap as a Screening Tool for Elevated Lactate in Patients with an Increased Risk of Developing Sepsis in the Emergency Department

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.8K citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +15

Serum Lactate as a Predictor of Mortality in Emergency Department Patients with Infection

Nathan I. Shapiro, Michael D. Howell, Daniel Talmor et al. · Annals of Emergency Medicine · 2005 · 755 citations

Veterinary Medicine, Emergency Medicine, Infectious Diseases +12

Blood Lactate Levels Are Superior to Oxygen-Derived Variables in Predicting Outcome in Human Septic Shock

Jan Bakker, M Coffernils, Marc Léon et al. · CHEST Journal · 1991 · 725 citations

Veterinary Medicine, Physiology, Resuscitation +14

Base excess and lactate as prognostic indicators for patients admitted to intensive care

Iain M Smith, Pankaj Kumar, Síle F. Molloy et al. · Intensive Care Medicine · 2001 · 411 citations

Veterinary Medicine, Critical Care Nursing, Critical Care Medicine +12

Unmeasured anions in critically ill patients: Can they predict mortality?*

Jens Rocktaeschel, Hiroshi Morimatsu, Shigehiko Uchino et al. · Critical Care Medicine · 2003 · 175 citations

Life Sciences, Biochemistry, Critical Care Medicine +16