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Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis

InflammationChronic Inflammatory DiseasesAnti-inflammatoryAnti-inflammatory AgentsNon-steroidal Anti-inflammatory DrugMedicineImmunologyGastroenterologyChronic InflammationPathologyUlcerative ColitisPharmacologyProstaglandins E2Rheumatoid Arthritis-Dependent Exacerbation