Association Between Duration of Untreated Psychosis, Premorbid Functioning, and Cognitive Performance and the Outcome of First-Episode Schizophrenia in Japanese Patients: Prospective Study

Abstract

The present results in a Japanese sample are consistent with previous international evidence that delay of initial treatment, premorbid functioning, and cognitive deficits are associated with outcome. A major limitation of the present study was the small size of the subject group. But because the subjects were relatively homogeneous and not influenced by psychoactive substances, the results reflect the essence of the disorder.