Concepedia

Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2′-deoxyguanosine by high-performance liquid chromatography–electrospray tandem mass spectrometry as a measure of oxidative stress

Bhaskar Malayappan, Timothy J. Garrett, Mark S. Segal, Christiaan Leeuwenburgh

Journal of Chromatography A · 2007 · 78 citations · 26 references

DOI

Concepts

References

26

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry · 1992 · 1.8K citations · Full text

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

Mark K. Shigenaga, Carlos J. Gimeno, B N Ames · Proceedings of the National Academy of Sciences · 1989 · 733 citations · Full text

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[2] Assays of oxidative DNA damage biomarkers 8-oxo-2′-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection

Mark K. Shigenaga, Elias Aboujaoude, Qin Chen et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1994 · 298 citations

, , +14

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Kazuhiro Honda, Mark A. Smith, Xiongwei Zhu et al. · Journal of Biological Chemistry · 2005 · 284 citations · Full text

Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry

Allan Weimann · Nucleic Acids Research · 2002 · 251 citations · Full text