Pharmacology of Intravenous Insulin Administration: Implications for Future Closed-Loop Glycemic Control by the Intravenous/Intravenous Route

Abstract

We found that intravenous bolus injections of insulin lowered blood glucose levels rapidly and predictably. Repetitive small intravenous insulin boluses together with an accurate and fast-responding intravascular continuous glucose monitor should be studied as a method of closed-loop glycemic control.