Preparation of Foot and Mouth Disease trivalent vaccine type A, O, SAT2 and determination of the Guinea pig protective dose 50 (GPPD50)

Abstract

Aim: To determine the minimal effective dose of Foot and Mouth disease (FMD) serotypes (A, O, SAT2) according to antigenic content (146S) in order to produce a potent trivalent FMD vaccine.