Cyclic Sulfamidates as Vehicles for the Synthesis of Poly- and Diversely Substituted Benzosultams via Unusual S(O)₂−O Bond Cleavage

Abstract

1,2-Cyclic sulfamidates undergo novel, efficient, and regiospecific intramolecular nucleophilic cleavage with aryllithiated species to provide an entry to poly-, diversely, and enantiopure N-substituted benzosultams.