Transient Hyperglycemia Affects the Extent of Ischemia-Reperfusion-induced Renal Injury in Rats

Abstract

Hyperglycemia that occurred during renal ischemia-reperfusion resulted in severe functional injury compared with normoglycemia or with hyperglycemia that occurred after reperfusion. Investigated molecular pathways are more profoundly affected by hyperglycemia that occurs before renal ischemia-reperfusion.