Penicillin Resistance is Not Extrapolable to Amoxicillin Resistance in <i>Streptococcus Pneumoniae</i> Isolated from Middle Ear Fluid in Children with Acute Otitis Media

Abstract

Penicillin resistance is not extrapolable to amoxicillin among S pneumoniae strains isolated from middle ear fluid of children with AOM. Our results support the recommendation to evaluate the minimal inhibitory concentrations of penicillin-nonsusceptible S pneumoniae for amoxicillin and to continue use of this antimicrobial as a first-line antimicrobial choice for children with AOM.