Hypoxia inducible factor‐1α induction by tumour necrosis factor‐α, but not by toll‐like receptor agonists, modulates cellular respiration in cultured human hepatocytes

Abstract

The data suggest that HIF-1 alpha modulates mitochondrial respiration during CoCl(2) and TNF-alpha stimulation, whereas it has no effect when induced with TLR-2, -3 and -4 agonists.