Endothelial dysfunction in the early stage of atherosclerosis precedes appearance of intimal lesions assessable with intravascular ultrasound

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries

Paul L. Ludmer, Andrew P. Selwyn, Thomas Shook et al. · New England Journal of Medicine · 1986 · 2.4K citations

Medicine, Cardiology, Pharmacology +16

Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.

Andreas M. Zeiher, H. Drexler, H. Wollschläger et al. · Circulation · 1991 · 995 citations

Medicine, Cardiology, Physiology +17

Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

Kiyotaka Kugiyama, Scott Kerns, Joel D. Morrisett et al. · Nature · 1990 · 858 citations

Life Sciences, Biochemistry, Physiology +9

Intravascular ultrasound assessment of lumen size and wall morphology in normal subjects and patients with coronary artery disease.

S.E. Nissen, John C. Gurley, Cindy L. Grines et al. · Circulation · 1991 · 666 citations · Full text

Medicine, Cardiology, Radiology +17